sildenafil for the treatment of lymphatic malformations.
Lymphatic Malformations can be very challenging for the clinician to treat. Interventions include sclerotherapy and surgery are invasive and may result in complications and recurrence of the lesion. A new study published in the Journal of the American Academy of Dermatology 2014 March 20 pii: S0190-9622(14)0119-0 examines sildenafil generic for viagra to treat lymphatic malformations.
Patients were placed on 20 weeks of oral sildenafil, LM were assessed for volum and symptoms. Sever male children and 3 females were observed; ages 13-85 months. There was a therapeutic response of softening and compressiblity in all patients. Adverse events were minimal. A larger randomized controlled study is needed to better verify these results however; it seems sildenafil may reduce lymphatic malformation volume and symptoms in some patients.
J Am Acad Dermatol. 2014 Mar 20. pii: S0190-9622(14)01119-0. doi: 10.1016/j.jaad.2014.02.005. [Epub ahead of print]
An open-label study to evaluate sildenafil for the treatment of lymphatic malformations.
- 1Department of Dermatology, Lucile Packard Children’s Hospital at the Stanford University School of Medicine, Palo Alto.
- 2Department of Radiology, Stanford University School of Medicine, Stanford.
- 3Department of Dermatology, Lucile Packard Children’s Hospital at the Stanford University School of Medicine, Palo Alto. Electronic address: firstname.lastname@example.org.